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Fattening the role of Ca2+ cycling in adaptive thermogenesis

Nature Medicine volume 23, pages 1403–1404 (2017)Cite this article

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A new study shows that deleting uncoupling protein 1 activates Ca2+ cycling thermogenesis within beige fat, protecting mice against cold-induced hypothermia and dysglycemia following diet-induced obesity.

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Figure 1: Ca2+ cycling thermogenesis is used by beige fat and skeletal muscle to regulate core body temperature, body mass and metabolism.

Katie Vicari/Springer Nature

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Authors and Affiliations

  1. the Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada

    Daniel Gamu & A Russell Tupling

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  1. Daniel Gamu
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  2. A Russell Tupling
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Correspondence to A Russell Tupling.

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Gamu, D., Tupling, A. Fattening the role of Ca2+ cycling in adaptive thermogenesis. Nat Med 23, 1403–1404 (2017). https://doi.org/10.1038/nm.4457

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