Macrophages dispose of catecholamines in adipose tissue

Recent research has identified sympathetic neuron–associated macrophages in adipose tissue that take up and degrade catecholamines released from neurons. Obesity and aging enhance this system, decreasing responses to cold stress and starvation.

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Figure 1: The role of NE-degrading macrophages in obesity and aging.

Katie Vicari/Springer Nature

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Correspondence to Michael P Czech.

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Czech, M. Macrophages dispose of catecholamines in adipose tissue. Nat Med 23, 1255–1257 (2017). https://doi.org/10.1038/nm.4440

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