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Imaging biomarkers and biotypes for depression

Nature Medicine volume 23, pages 16–17 (2017)Cite this article

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A new study identifies four distinct 'biotypes' of depression on the basis of fMRI resting-state functional connectivity in a diverse sample of more than 1,000 individuals. The biotypes are diagnostic of depression and predict treatment response.

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Figure 1: Biotypes and biomarkers for depression.

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References

  1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders–5 (American Psychiatric Association, 2013).

  2. Regier, D.A. et al. Am. J. Psychiatry 170, 59–70 (2013).

    Article  Google Scholar 

  3. Rosenhan, D.L. Science 179, 250–258 (1973).

    Article  CAS  Google Scholar 

  4. Sanislow, C.A. et al. J. Abnorm. Psychol. 119, 631–639 (2010).

    Article  Google Scholar 

  5. Collins, F.S. & Varmus, H. N. Engl. J. Med. 372, 793–795 (2015).

    Article  CAS  Google Scholar 

  6. Drysdale, A.T. et al. Nat. Med. 23, 28–38 (2017).

    Article  CAS  Google Scholar 

  7. Pereira, F., Mitchell, T. & Botvinick, M. Neuroimage 45 (Suppl.), S199–S209 (2009).

    Article  Google Scholar 

  8. Wager, T.D. et al. N. Engl. J. Med. 368, 1388–1397 (2013).

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Jordan, M.I. & Mitchell, T.M. Science 349, 255–260 (2015).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Tor D. Wager and Choong-Wan Woo are in the Department of Psychology and Neuroscience, University of Colorado, Boulder, Boulder, Colorado, USA.,

    Tor D Wager & Choong-Wan Woo

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  1. Tor D Wager
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  2. Choong-Wan Woo
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Correspondence to Tor D Wager.

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The authors declare no competing financial interests.

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Wager, T., Woo, CW. Imaging biomarkers and biotypes for depression. Nat Med 23, 16–17 (2017). https://doi.org/10.1038/nm.4264

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