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A bone marrow factor contributes to kidney disease

Nature Medicine volume 23, pages 13–14 (2017)Cite this article

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Soluble urokinase plasminogen activator receptor (suPAR) is a circulating biomarker of inflammation. A recent study identifies immature myeloid cells in the bone marrow as a major cellular source of suPAR that contributes to kidney disease.

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Figure 1: Immature myeloid cells produce suPAR mediating proteinuric kidney disease.

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  1. Stuart J. Shankland and J. Ashley Jefferson are in the Division of Nephrology, Department of Medicine, University of Washington, Seattle, Washington, USA.,

    Stuart J Shankland & J Ashley Jefferson

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  1. Stuart J Shankland
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  2. J Ashley Jefferson
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Correspondence to Stuart J Shankland.

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The authors declare no competing financial interests.

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Shankland, S., Jefferson, J. A bone marrow factor contributes to kidney disease. Nat Med 23, 13–14 (2017). https://doi.org/10.1038/nm.4263

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