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A microbial protein that alleviates metabolic syndrome

A recent study shows that pasteurization of Akkermansia muciniphila enhances the bacterium's ability to reduce fat mass and metabolic syndrome in mice with diet-induced obesity, and that Amuc_1100*, a thermostable outer-membrane protein of A. muciniphila, can reproduce these beneficial effects.

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Figure 1: Pasteurized Akkermansia muciniphila and its outer-membrane protein Amuc_1100* improve gut-barrier integrity and metabolic syndrome in mice with diet-induced obesity.

Marina Corral Spence/Springer Nature

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Correspondence to André Marette.

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Anhê, F., Marette, A. A microbial protein that alleviates metabolic syndrome. Nat Med 23, 11–12 (2017). https://doi.org/10.1038/nm.4261

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