Goldenberg, R.L., Culhane, J.F., Iams, J.D. & Romero, R. Epidemiology and causes of preterm birth. Lancet 371, 75–84 (2008).
Romero, R. et al. The preterm parturition syndrome. BJOG 113(Suppl. 3), 17–42 (2006).
Jensen, F. et al. CD19+CD5+ cells as indicators of preeclampsia. Hypertension 59, 861–868 (2012).
Zhou, C.C. et al. Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice. Nat. Med. 14, 855–862 (2008).
Matthiesen, L. et al. Immunology of preeclampsia. in Immunology of Pregnancy, Vol. 89 (ed. Markert, U.R.) 49–61 (Karger, Basel, 2005).
Frank, H.G. & Kaufmann, P. Nonvillous parts and trophoblast invasion. in Pathology of the Human Placenta (eds. Benirschke, K., Kaufmann, P. & Baergen, R.N.) 191–287 (Springer, New York, NY, 2006).
Trundley, A. & Moffett, A. Human uterine leukocytes and pregnancy. Tissue Antigens 63, 1–12 (2004).
Moffett, A. & Shreeve, N. First do no harm: uterine natural killer (NK) cells in assisted reproduction. Hum. Reprod. 30, 1519–1525 (2015).
Martin, N.T. & Martin, M.U. Interleukin 33 is a guardian of barriers and a local alarmin. Nat. Immunol. 17, 122–131 (2016).
Muzzio, D.O. et al. B cell development undergoes profound modifications and adaptations during pregnancy in mice. Biol. Reprod. 91, 115 (2014).
Zimmer, J.P., Garza, C., Butte, N.F. & Goldman, A.S. Maternal blood B-cell (CD19+) percentages and serum immunoglobulin concentrations correlate with breast-feeding behavior and serum prolactin concentration. Am. J. Reprod. Immunol. 40, 57–62 (1998).
Bhat, N.M., Mithal, A., Bieber, M.M., Herzenberg, L.A. & Teng, N.N. Human CD5+ B lymphocytes (B-1 cells) decrease in peripheral blood during pregnancy. J. Reprod. Immunol. 28, 53–60 (1995).
Medina, K.L. & Kincade, P.W. Pregnancy-related steroids are potential negative regulators of B lymphopoiesis. Proc. Natl. Acad. Sci. USA 91, 5382–5386 (1994).
Reiss, Y., Proudfoot, A.E., Power, C.A., Campbell, J.J. & Butcher, E.C. CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin. J. Exp. Med. 194, 1541–1547 (2001).
Mora, J.R. et al. Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 424, 88–93 (2003).
Homey, B. et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat. Med. 8, 157–165 (2002).
Griffin, D.O., Holodick, N.E. & Rothstein, T.L. Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70−. J. Exp. Med. 208, 67–80 (2011).
Litinskiy, M.B. et al. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat. Immunol. 3, 822–829 (2002).
Xu, W. et al. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nat. Immunol. 8, 294–303 (2007).
Candando, K.M., Lykken, J.M. & Tedder, T.F. B10 cell regulation of health and disease. Immunol. Rev. 259, 259–272 (2014).
Rosser, E.C. & Mauri, C. Regulatory B cells: origin, phenotype, and function. Immunity 42, 607–612 (2015).
Robertson, S.A., Skinner, R.J. & Care, A.S. Essential role for IL-10 in resistance to lipopolysaccharide-induced preterm labor in mice. J. Immunol. 177, 4888–4896 (2006).
Thaxton, J.E., Romero, R. & Sharma, S. TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes. J. Immunol. 183, 1144–1154 (2009).
Tian, J. et al. Lipopolysaccharide-activated B cells down-regulate Th1 immunity and prevent autoimmune diabetes in nonobese diabetic mice. J. Immunol. 167, 1081–1089 (2001).
Parekh, V.V. et al. B cells activated by lipopolysaccharide, but not by anti-Ig and anti-CD40 antibody, induce anergy in CD8+ T cells: role of TGF-beta 1. J. Immunol. 170, 5897–5911 (2003).
Shen, P. et al. IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature 507, 366–370 (2014).
Wang, R.X. et al. Interleukin-35 induces regulatory B cells that suppress autoimmune disease. Nat. Med. 20, 633–641 (2014).
Collison, L.W. et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450, 566–569 (2007).
Romero, R., Yeo, L., Chaemsaithong, P., Chaiworapongsa, T. & Hassan, S.S. Progesterone to prevent spontaneous preterm birth. Semin. Fetal Neonatal Med. 19, 15–26 (2014).
Szekeres-Bartho, J. & Polgar, B. PIBF: the double edged sword. Pregnancy and tumor. Am. J. Reprod. Immunol. 64, 77–86 (2010).
Hudić, I. et al. Maternal serum progesterone-induced blocking factor (PIBF) in the prediction of preterm birth. J. Reprod. Immunol. 109, 36–40 (2015).
Polgar, B. et al. Molecular cloning and immunologic characterization of a novel cDNA coding for progesterone-induced blocking factor. J. Immunol. 171, 5956–5963 (2003).
Lachmann, M. et al. PIBF (progesterone induced blocking factor) is overexpressed in highly proliferating cells and associated with the centrosome. Int. J. Cancer 112, 51–60 (2004).
Gonzalez-Arenas, A., Valadez-Cosmes, P., Jimenez-Arellano, C., Lopez-Sanchez, M. & Camacho-Arroyo, I. Progesterone-induced blocking factor is hormonally regulated in human astrocytoma cells, and increases their growth through the IL-4R/JAK1/STAT6 pathway. J. Steroid Biochem. Mol. Biol. 144 Pt B, 463–470 (2014).
Szekeres-Bartho, J. et al. The mechanism of the inhibitory effect of progesterone on lymphocyte cytotoxicity. I. Progesterone-treated lymphocytes release a substance inhibiting cytotoxicity and prostaglandin synthesis. Am. J. Reprod. Immunol. Microbiol. 9, 15–18 (1985).
Schiering, C. et al. The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature 513, 564–568 (2014).
Sattler, S. et al. IL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut. J. Autoimmun. 50, 107–122 (2014).
Burzyn, D. et al. A special population of regulatory T cells potentiates muscle repair. Cell 155, 1282–1295 (2013).
Bapat, S.P. et al. Depletion of fat-resident Treg cells prevents age-associated insulin resistance. Nature 528, 137–141 (2015).
Arpaia, N. et al. A distinct function of regulatory T cells in tissue protection. Cell 162, 1078–1089 (2015).
Chen, K. et al. Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils. Nat. Immunol. 10, 889–898 (2009).