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Fatty acid metabolism—the first trigger for cachexia?

Nature Medicine volume 22, pages 584–585 (2016)Cite this article

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A recent study shows that skeletal muscle responds to tumor-secreted factors by undergoing a change in fatty acid metabolism, and that blocking this metabolic response in mice inhibits muscle wasting.

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Figure 1: The cellular and molecular events that underlie cachexia.

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  1. David A. Sassoon is in the Stem Cells and Regenerative Medicine, UMRS 1166, Institute for Cardiometabolism and Nutrition (ICAN), University of Pierre and Marie Curie, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.,

    David A Sassoon

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  1. David A Sassoon
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Correspondence to David A Sassoon.

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Sassoon, D. Fatty acid metabolism—the first trigger for cachexia?. Nat Med 22, 584–585 (2016). https://doi.org/10.1038/nm.4121

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