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Fatty acid metabolism—the first trigger for cachexia?

Nature Medicine volume 22, pages 584585 (2016) | Download Citation

A recent study shows that skeletal muscle responds to tumor-secreted factors by undergoing a change in fatty acid metabolism, and that blocking this metabolic response in mice inhibits muscle wasting.

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References

  1. 1.

    , & Cell Metab. 16, 153–166 (2012).

  2. 2.

    et al. Nat. Med. 22, 666–671 (2016).

  3. 3.

    et al. Clin. Nutr. 27, 793–799 (2008).

  4. 4.

    Future Oncol. 6, 503–513 (2010).

  5. 5.

    , & Nat. Med. 21, 854–862 (2015).

  6. 6.

    et al. Nat. Med. 20, 265–271 (2014).

  7. 7.

    & Biochem. Pharmacol. 36, 3917–3921 (1987).

  8. 8.

    et al. Skelet. Muscle 6, 9 (2016).

  9. 9.

    & Skelet. Muscle 6, 1 (2015).

Download references

Author information

Affiliations

  1. David A. Sassoon is in the Stem Cells and Regenerative Medicine, UMRS 1166, Institute for Cardiometabolism and Nutrition (ICAN), University of Pierre and Marie Curie, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.

    • David A Sassoon

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Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to David A Sassoon.

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DOI

https://doi.org/10.1038/nm.4121

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