Adipocyte progenitors have the capacity to differentiate into mature brown adipocytes with thermogenic capabilities. Two new studies identify novel markers to help prospectively isolate these and mature adipocytes from human brown fat biopsies.
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van Marken Lichtenbelt, W.D. et al. N. Engl. J. Med. 360, 1500–1508 (2009).
Cypess, A.M. et al. N. Engl. J. Med. 360, 1509–1517 (2009).
Saito, M. et al. Diabetes 58, 1526–1531 (2009).
Virtanen, K.A. et al. N. Engl. J. Med. 360, 1518–1525 (2009).
Ouellet, V. et al. J. Clin. Invest. 122, 545–552 (2012).
Shinoda, K. et al. Nat. Med. 21, 389–394 (2015).
Xue R., et al. Nat Med. 21, 760–768 (2015).
Cypess, A.M. et al. Cell Metab. 21, 33–38 (2015).
van der Lans, A.A. et al. J. Clin. Invest. 123, 3395–3403 (2013).
Vijgen, G.H. et al. J. Clin. Endocrinol. Metab. 97, E1229–E1233 (2012).
Wu, J. et al. Cell 150, 366–376 (2012).
Cypess, A.M. et al. Nat. Med. 19, 635–639 (2013).
The authors declare no competing financial interests.
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Boon, M., Nascimento, E. & van Marken Lichtenbelt, W. Tracing human brown fat. Nat Med 21, 667–668 (2015). https://doi.org/10.1038/nm.3900