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Unpleasant memories: tissue-embedded T cell memory drives skin hypersensitivity

Nature Medicine volume 21, pages 551552 (2015) | Download Citation

Tissue-resident memory T cells (TRM cells) protect against recurrent or renewed infection in barrier tissues such as skin and mucosa. A new study sheds light on the clonal origin of TRM cells and demonstrates a crucial role for tissue-embedded T cell memory in contact hypersensitivity in skin.

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Author information

Affiliations

  1. Thomas Gebhardt and Francis R. Carbone are in the Department of Microbiology and Immunology, The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.

    • Thomas Gebhardt
    •  & Francis R Carbone

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Thomas Gebhardt.

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DOI

https://doi.org/10.1038/nm.3874

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