In the liver there is a fine balance between immune surveillance of blood-borne infections and regulation of immunopathology. A new study identifies a role for granulocytic myeloid-derived suppressor cells in limiting T cell–mediated immunopathology in hepatitis B virus infection.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Attenuated viral hepatitis in Trem1−/− mice is associated with reduced inflammatory activity of neutrophils
Scientific Reports Open Access 22 June 2016
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Kim Caesar/Nature Publishing Group
References
Jenne, C.N. & Kubes, P. Nat. Immunol. 14, 996–1006 (2013).
Barnaba, V., Paroli, M. & Piconese, S. Front. Immunol. 3, 18 (2012).
Pallett, L.J. et al. Nat. Med. 21, 591–600 (2015).
Wherry, E.J. Nat. Immunol. 12, 492–499 (2011).
Solito, S. et al. Blood 118, 2254–2265 (2011).
Rodriguez, P.C. et al. Cancer Res. 69, 1553–1560 (2009).
Sato, S. et al. Immunity 42, 123–132 (2015).
Chiu, Y.S., Wei, C.C., Lin, Y.J., Hsu, Y.H. & Chang, M.S. Hepatology 60, 1003–1014 (2014).
Liu, G. et al. J. Immunol. 192, 3068–3079 (2014).
Noman, M.Z. et al. J. Exp. Med. 211, 781–790 (2014).
Franceschini, D. et al. J. Clin. Invest. 119, 551–564 (2009).
Piconese, S. et al. Hepatology 60, 1494–1507 (2014).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Piconese, S., Barnaba, V. Regulation of immunopathology in hepatitis B virus infection. Nat Med 21, 548–549 (2015). https://doi.org/10.1038/nm.3873
Published:
Issue Date:
DOI: https://doi.org/10.1038/nm.3873
