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A mediator for malaria stickiness in A versus O blood

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Malaria is thought to have shaped the worldwide distribution of human ABO blood but the underlying molecular details of this process have only recently started to be revealed. A new study provides insights on how malaria parasites interact with ABO blood group sugars, mediating rosetting events that cause severe disease.

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Figure 1: RIFINs and the rosetting phenotype.

Kim Caesar/Nature Publishing Group

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Correspondence to Maria M Mota.

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The authors declare no competing financial interests.

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Mancio-Silva, L., Mota, M. A mediator for malaria stickiness in A versus O blood. Nat Med 21, 307–308 (2015). https://doi.org/10.1038/nm.3837

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