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Taming the inflammasome

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The NLRP3 inflammasome is involved in the molecular etiology of multiple autoinflammatory diseases. Two studies identify inhibitors of NLRP3 activation and might pave the way for new treatment options for a variety of diseases.

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Figure 1: Inhibitors of the NLRP3 inflammasome.

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Correspondence to Eran Elinav.

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Levy, M., Thaiss, C. & Elinav, E. Taming the inflammasome. Nat Med 21, 213–215 (2015). https://doi.org/10.1038/nm.3808

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