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Understanding Local Macrophage Phenotypes In Disease: Shape-shifting macrophages

Macrophages are responsive to local tissue signals and alter their phenotypes accordingly. In disease tissues this means that macrophage phenotypes may change with disease progression, exacerbating or facilitating the resolution of the pathology.

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Figure 1: The plasticity of macrophages.

Marina Corral Spence / Nature Publishing Group

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Correspondence to Philip R Taylor.

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Liddiard, K., Taylor, P. Understanding Local Macrophage Phenotypes In Disease: Shape-shifting macrophages. Nat Med 21, 119–120 (2015). https://doi.org/10.1038/nm.3798

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