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Reducing peripheral serotonin turns up the heat in brown fat

Nature Medicine volume 21, pages 114116 (2015) | Download Citation

Obesity is a major risk factor for chronic disease. A new study in mice reveals that lowering levels of the signaling molecule serotonin outside of the brain reduces obesity and its complications by increasing brown adipose tissue (BAT) energy expenditure.

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Author information

Affiliations

  1. Andrew L. Carey and Bronwyn A. Kingwell are in the Metabolic and Vascular Physiology Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Australia.

    • Andrew L Carey
    •  & Bronwyn A Kingwell

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Bronwyn A Kingwell.

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DOI

https://doi.org/10.1038/nm.3797

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