Obesity is a major risk factor for chronic disease. A new study in mice reveals that lowering levels of the signaling molecule serotonin outside of the brain reduces obesity and its complications by increasing brown adipose tissue (BAT) energy expenditure.
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Carey, A., Kingwell, B. Reducing peripheral serotonin turns up the heat in brown fat. Nat Med 21, 114–116 (2015). https://doi.org/10.1038/nm.3797
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DOI: https://doi.org/10.1038/nm.3797