Regulation of glucose homeostasis using radiogenetics and magnetogenetics in mice

Endogenous expression of tailored nanoparticles in cells followed by application of low-frequency radio waves or a magnetic field can be used to noninvasively modulate gene expression. This approach successfully induces insulin transgene expression in diabetic mice.

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Figure 1: Activation of insulin expression in the liver by radio waves or magnetic field.

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Correspondence to Per-Olof Berggren.

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Leibiger, I., Berggren, P. Regulation of glucose homeostasis using radiogenetics and magnetogenetics in mice. Nat Med 21, 14–16 (2015) doi:10.1038/nm.3782

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