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Regulation of glucose homeostasis using radiogenetics and magnetogenetics in mice

Nature Medicine volume 21, pages 14–16 (2015)Cite this article

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Endogenous expression of tailored nanoparticles in cells followed by application of low-frequency radio waves or a magnetic field can be used to noninvasively modulate gene expression. This approach successfully induces insulin transgene expression in diabetic mice.

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Figure 1: Activation of insulin expression in the liver by radio waves or magnetic field.

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Authors and Affiliations

  1. Ingo B. Leibiger and Per-Olof Berggren are at The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.,

    Ingo B Leibiger & Per-Olof Berggren

  2. Per-Olof Berggren is also affiliated with the Lee Kong Chian School of Medicine, Nanyang Technological University, Imperial College London, Novena Campus, Singapore.,

    Per-Olof Berggren

Authors
  1. Ingo B Leibiger
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  2. Per-Olof Berggren
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Correspondence to Per-Olof Berggren.

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The authors declare no competing financial interests.

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Leibiger, I., Berggren, PO. Regulation of glucose homeostasis using radiogenetics and magnetogenetics in mice. Nat Med 21, 14–16 (2015). https://doi.org/10.1038/nm.3782

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