A new study identifies recurrent somatic duplications of a NOTCH1-driven enhancer of MYC in human T cell leukemia. This enhancer is required for both normal and malignant T cell development.
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Pouliot, G., Gutierrez, A. Thymocyte transformation enhanced. Nat Med 20, 1096–1097 (2014). https://doi.org/10.1038/nm.3711
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DOI: https://doi.org/10.1038/nm.3711