Stress has long been thought to be a major contributing factor to cardiovascular disease, although little is known about the underlying cellular mechanisms. A new study in humans and mice suggests that chronic stress promotes hematopoietic stem cell proliferation in bone marrow, leading to increased leukocyte production, circulation and recruitment to the vasculature (pages 754–758).
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Hanna, R., Hedrick, C. Stressing out stem cells: linking stress and hematopoiesis in cardiovascular disease. Nat Med 20, 707–708 (2014). https://doi.org/10.1038/nm.3631
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DOI: https://doi.org/10.1038/nm.3631
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