In fragile X syndrome, the absence of fragile X mental retardation protein (FMRP) allows the production of certain proteins to go unchecked in the brain. A recent study in mice suggests that bringing excessive translation into balance may provide a key to treating this syndrome (pages 1473–1477).
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Smith, L., Cowan, C. Striking a balance in fragile X. Nat Med 19, 1370–1371 (2013). https://doi.org/10.1038/nm.3383
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DOI: https://doi.org/10.1038/nm.3383
