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The origin of scar-forming kidney myofibroblasts


Whereas diabetes and hypertension predominate as the etiology of chronic kidney disease (CKD), all primary causes share a common progression pathway due to scarring or fibrosis. Understanding what cells are the sources of scar-forming cells is of utmost importance (pages 1047–1053).

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Figure 1: Origin of scar-associated kidney myofibroblasts.

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Correspondence to Allison A Eddy.

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Eddy, A. The origin of scar-forming kidney myofibroblasts. Nat Med 19, 964–966 (2013).

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