A new study establishes a link between glucagon-like peptide-1 (GLP-1) release from the gut and the cardiac hormone atrial natriuretic peptide, which lowers blood pressure. As GLP-1 receptor agonists are used to control glycemia in patients with type 2 diabetes, this new gut-heart axis suggests a role of these agents in overall cardiovascular homeostasis (pages 567–575).
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Buglioni, A., Burnett, J. A gut-heart connection in cardiometabolic regulation. Nat Med 19, 534–536 (2013). https://doi.org/10.1038/nm.3196
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DOI: https://doi.org/10.1038/nm.3196
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