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Hiding under the skin: A welcome surprise in psoriasis

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Figure 1: Skin inflammation in patients with psoriasis and mouse models of disease.

Debbie Maizels


  1. Steinman, L. Nat. Med. 13, 139–145 (2007).

    Article  CAS  Google Scholar 

  2. Nestle, F.O., Kaplan, D.H. & Barker, J. N. Engl. J. Med. 361, 496–509 (2009).

    Article  CAS  Google Scholar 

  3. Farley, E. & Menter, A. G. Ital. Dermatol. Venereol. 146, 9–15 (2011).

    CAS  PubMed  Google Scholar 

  4. Suárez-Fariñas, M. et al. J. Invest. Dermatol. 132, 2552–2564 (2012).

    Article  Google Scholar 

  5. Johnson-Huang, L.M., Lowes, M.A. & Krueger, J.G. Dis. Model. Mech. 5, 423–433 (2012).

    Article  CAS  Google Scholar 

  6. Zheng, Y. et al. Nature 445, 648–651 (2007).

    Article  CAS  Google Scholar 

  7. Van Belle, A.B. et al. J. Immunol. 188, 462–469 (2012).

    Article  CAS  Google Scholar 

  8. Leonardi, C. et al. N. Engl. J. Med. 366, 1190–1199 (2012).

    Article  CAS  Google Scholar 

  9. Papp, K.A. et al. N. Engl. J. Med. 366, 1181–1189 (2012).

    Article  CAS  Google Scholar 

  10. Krueger, J. G. et al. J. Allergy Clin. Immunol. 130, 145–154.e9 (2012).

    Article  CAS  Google Scholar 

  11. Cua, D.J. et al. Nature 421, 744–748 (2003).

    Article  CAS  Google Scholar 

  12. Ding, H.S. et al. Mol. Biol. Rep. 39, 7473–7478 (2012).

    Article  CAS  Google Scholar 

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Correspondence to James G Krueger.

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Competing interests

J.G.K. is a consultant to Eli Lilly, Amgen and Novartis (all are testing IL-17 antagonists in psoriasis).

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Krueger, J. Hiding under the skin: A welcome surprise in psoriasis. Nat Med 18, 1750–1751 (2012).

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