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The tumor microenvironment controls drug sensitivity

Nature Medicine volume 18, pages 13321334 (2012) | Download Citation

A better understanding of mechanisms involved in regulation of drug sensitivity is crucial for improved cancer treatment. New studies show that cells of the tumor microenvironment modulate the response of cancer cells to chemotherapy and targeted therapies through production of secreted factors (pages 1359–1368).

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Author information

Affiliations

  1. Arne Östman is in the Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

    • Arne Östman

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Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to Arne Östman.

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DOI

https://doi.org/10.1038/nm.2938

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