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The tumor microenvironment controls drug sensitivity

A better understanding of mechanisms involved in regulation of drug sensitivity is crucial for improved cancer treatment. New studies show that cells of the tumor microenvironment modulate the response of cancer cells to chemotherapy and targeted therapies through production of secreted factors (pages 1359–1368).

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Figure 1: Tumor microenvironment regulates drug sensitivity.

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Correspondence to Arne Östman.

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Östman, A. The tumor microenvironment controls drug sensitivity. Nat Med 18, 1332–1334 (2012). https://doi.org/10.1038/nm.2938

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