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Quantifying the activity of anti-HIV treatment in silico

Combination-based antiretroviral therapy has been very successful in preventing disease progression in HIV-infected individuals. However, a rational method for predicting the effect of a particular drug combination on clinical outcome is needed. A new study takes us closer to this goal by computationally predicting the inhibitory effects of combinations of three antiretroviral drugs (pages 446–451).

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Figure 1: Devising a quantitative model to predict inhibition of HIV-1 infection by combinations of antiretroviral drugs.


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Correspondence to Ruy M Ribeiro.

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Ribeiro, R. Quantifying the activity of anti-HIV treatment in silico. Nat Med 18, 355–356 (2012).

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