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Stressed tumor cell, chemosensitized cancer

Nature Medicine volume 17, pages 15521554 (2011) | Download Citation

miR-200 family expression results in highly proliferative ovarian cancer cells. Yet this expression is also linked to longer overall survival in women with ovarian cancer. A new study sheds light into this apparent paradox showing that two members of this family—miR-141 and miR-200a—not only boost tumor growth but also sensitize tumor cells to chemotherapy (pages 1627–1635).

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Author information

Affiliations

  1. Erik A.C. Wiemer is at the Erasmus Medical Center, Daniel den Hoed Cancer Center, Department of Medical Oncology, Rotterdam, The Netherlands.

    • Erik A C Wiemer

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The author declares no competing financial interests.

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Correspondence to Erik A C Wiemer.

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DOI

https://doi.org/10.1038/nm.2593

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