SGK1: a fine balancing act for human pregnancy

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A new study suggests that regulation of the serum- and glucocorticoid-regulated kinase (SGK1) is important for ensuring uterine receptivity and maintenance of pregnancy (pages 1509–1513). Additional work will be required to determine whether SGK1 could be potentially targeted to treat infertility and prevent miscarriage and whether it can be used as a biomarker.

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Figure 1: Balancing SGK1 expression to regulate pregnancy.

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Correspondence to Susan J Fisher or Linda C Giudice.

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