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EGFR signaling in podocytes at the root of glomerular disease

Nature Medicine volume 17, pages 11881189 (2011) | Download Citation

A study in a mouse model of immune-mediated glomerular disease and in people with rapidly progressive glomerulonephritis shows activation of epidermal growth factor receptor (EFGR) signaling in podocytes by a molecule expressed in the kidney (pages 1242–1250). Blocking this axis may open new doors to treat inflammatory kidney conditions.

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Author information

Affiliations

  1. Ray Harris is at the Division of Nephrology and Hypertension, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

    • Ray Harris

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Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to Ray Harris.

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DOI

https://doi.org/10.1038/nm.2455

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