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A new human immunodeficiency virus derived from gorillas

Nature Medicine volume 15, pages 871–872 (2009)Cite this article

Abstract

We have identified a new human immunodeficiency virus in a Cameroonian woman. It is closely related to gorilla simian immunodeficiency virus (SIVgor) and shows no evidence of recombination with other HIV-1 lineages. This new virus seems to be the prototype of a new HIV-1 lineage that is distinct from HIV-1 groups M, N and O. We propose to designate it HIV-1 group P.

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Figure 1: Evolutionary relationship of strain RBF168 to HIV-1, SIVcpz and SIVgor.

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Acknowledgements

We thank H. Ichou for field assistance and all the staff of the Rouen Virology Laboratory. Funding was provided by Institut de Veille Sanitaire, Agence Nationale de Recherches sur le Sida et les Hépatites and Rouen University Hospital, France. J.E.D. is supported by a Wellcome Trust studentship.

Author information

Authors and Affiliations

  1. Laboratoire associé au Centre National de Référence du Virus de l'Immunodéficience Humaine, Centre Hospitalier Universitaire de Rouen, Equipe d'Accueil EA2656, Faculté de Médecine-Pharmacie, Université de Rouen, France

    Jean-Christophe Plantier, Marie Leoz, Fabienne De Oliveira & Véronique Lemée

  2. Faculty of Life Sciences, University of Manchester, UK

    Jonathan E Dickerson & David L Robertson

  3. Hôpital Louis Mourier, Colombes, France

    François Cordonnier

  4. Hôpital Bichat, Paris, France

    Florence Damond

  5. Hôpital Saint-Louis, Institut National de la Santé et de la Recherche Médicale U941, Faculté de Médecine, Université Paris-Diderot, Paris, France

    François Simon

Authors
  1. Jean-Christophe Plantier
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  2. Marie Leoz
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  3. Jonathan E Dickerson
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  4. Fabienne De Oliveira
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  5. François Cordonnier
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  6. Véronique Lemée
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  7. Florence Damond
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  8. David L Robertson
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  9. François Simon
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Contributions

J.-C.P., M.L. and F.D.O. conceived of and designed the experiments. M.L., F.D.O. and V.L. performed the molecular and serological experiments. J.E.D. and D.L.R. performed the computational analysis. F.C. managed the subject and collected epidemiological data. J.-C.P., V.L. and F.D. monitored the subject's virologic status. J.-C.P, M.L., J.E.D., F.D.O., D.L.R. and F.S. wrote the paper.

Corresponding author

Correspondence to Jean-Christophe Plantier.

Supplementary information

Supplementary Text and Figures

Supplementary Figures 1–5, Supplementary Tables 1 and 2 and Supplementary Methods (PDF 402 kb)

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Plantier, JC., Leoz, M., Dickerson, J. et al. A new human immunodeficiency virus derived from gorillas. Nat Med 15, 871–872 (2009). https://doi.org/10.1038/nm.2016

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  • DOI: https://doi.org/10.1038/nm.2016

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