Brief Communication

A new human immunodeficiency virus derived from gorillas

Received:
Accepted:
Published online:

Abstract

We have identified a new human immunodeficiency virus in a Cameroonian woman. It is closely related to gorilla simian immunodeficiency virus (SIVgor) and shows no evidence of recombination with other HIV-1 lineages. This new virus seems to be the prototype of a new HIV-1 lineage that is distinct from HIV-1 groups M, N and O. We propose to designate it HIV-1 group P.

  • Subscribe to Nature Medicine for full access:

    $225

    Subscribe

Additional access options:

Already a subscriber?  Log in  now or  Register  for online access.

Accessions

GenBank/EMBL/DDBJ

References

  1. 1.

    et al. Nature 397, 436–441 (1999).

  2. 2.

    et al. Science 313, 523–526 (2006).

  3. 3.

    et al. Nature 444, 164 (2006).

  4. 4.

    et al. J. Virol. 83, 1635–1648 (2009).

  5. 5.

    et al. Nat. Med. 4, 1032–1037 (1998).

  6. 6.

    et al. Science 288, 55–56 (2000).

  7. 7.

    et al. J. Acquir. Immune Defic. Syndr. 36, 639–641 (2004).

  8. 8.

    et al. J. Acquir. Immune Defic. Syndr. 45, 380–388 (2007).

  9. 9.

    et al. Mol. Biol. Evol. 24, 1853–1860 (2007).

Download references

Acknowledgements

We thank H. Ichou for field assistance and all the staff of the Rouen Virology Laboratory. Funding was provided by Institut de Veille Sanitaire, Agence Nationale de Recherches sur le Sida et les Hépatites and Rouen University Hospital, France. J.E.D. is supported by a Wellcome Trust studentship.

Author information

Affiliations

  1. Laboratoire associé au Centre National de Référence du Virus de l'Immunodéficience Humaine, Centre Hospitalier Universitaire de Rouen, Equipe d'Accueil EA2656, Faculté de Médecine-Pharmacie, Université de Rouen, France.

    • Jean-Christophe Plantier
    • , Marie Leoz
    • , Fabienne De Oliveira
    •  & Véronique Lemée
  2. Faculty of Life Sciences, University of Manchester, UK.

    • Jonathan E Dickerson
    •  & David L Robertson
  3. Hôpital Louis Mourier, Colombes, France.

    • François Cordonnier
  4. Hôpital Bichat, Paris, France.

    • Florence Damond
  5. Hôpital Saint-Louis, Institut National de la Santé et de la Recherche Médicale U941, Faculté de Médecine, Université Paris-Diderot, Paris, France.

    • François Simon

Authors

  1. Search for Jean-Christophe Plantier in:

  2. Search for Marie Leoz in:

  3. Search for Jonathan E Dickerson in:

  4. Search for Fabienne De Oliveira in:

  5. Search for François Cordonnier in:

  6. Search for Véronique Lemée in:

  7. Search for Florence Damond in:

  8. Search for David L Robertson in:

  9. Search for François Simon in:

Contributions

J.-C.P., M.L. and F.D.O. conceived of and designed the experiments. M.L., F.D.O. and V.L. performed the molecular and serological experiments. J.E.D. and D.L.R. performed the computational analysis. F.C. managed the subject and collected epidemiological data. J.-C.P., V.L. and F.D. monitored the subject's virologic status. J.-C.P, M.L., J.E.D., F.D.O., D.L.R. and F.S. wrote the paper.

Corresponding author

Correspondence to Jean-Christophe Plantier.

Supplementary information

PDF files

  1. 1.

    Supplementary Text and Figures

    Supplementary Figures 1–5, Supplementary Tables 1 and 2 and Supplementary Methods