Some well-funded researchers will soon have one fewer option for getting grants. Starting next year, the National Institute of General Medical Sciences in Bethesda, Maryland, will not award large grants to researchers who already have one. The goal is to spread sparse funds across more labs, says institute head Jon Lorsch. He estimates that the policy will free up about 25 grants a year to help launch labs or support ones in danger of closing. “We really want to have as diverse and broad a scientific portfolio as we can,” he says. “Any small amount is going to help the great scientists who are struggling.”