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Regulatory ripples

Nature Immunology volume 11, pages 10771078 (2010) | Download Citation

Regulatory T cells come in many different forms depending on their mode of action or developmental origin. Data now show that interleukin 35, an immunomodulatory cytokine secreted by regulatory T cells, and interleukin 10 induce so-called 'iTR35 cells', which may have an important role in the phenomenon of infectious tolerance.

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References

  1. 1.

    et al. Nat. Immunol. 11, 1093–1101 (2010).

  2. 2.

    et al. Immunol. Rev. 212, 28–50 (2006).

  3. 3.

    et al. J. Exp. Med. 198, 1875–1886 (2003).

  4. 4.

    et al. J. Exp. Med. 204, 1775–1785 (2007).

  5. 5.

    et al. Nature Immunology 10, 1–7 (2009).

  6. 6.

    et al. Nature 458, 351–356 (2009).

  7. 7.

    et al. Science 259, 974–977 (1993).

  8. 8.

    , , & Immunol. Rev. 212, 301–313 (2006).

  9. 9.

    et al. J. Exp. Med. 205, 1975–1981 (2008).

  10. 10.

    et al. Eur. J. Immunol. 37, 3021–3029 (2007).

  11. 11.

    et al. Nature 450, 566–569 (2007).

  12. 12.

    , , , & J. Immunol. 181, 6898–6905 (2008).

  13. 13.

    et al. Eur. J. Immunol. 40, 321–329 (2010).

  14. 14.

    et al. Immunity 31, 772–786 (2009).

Download references

Author information

Affiliations

  1. Yasmine Belkaid is with the Mucosal Immunology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

    • Yasmine Belkaid
  2. WanJun Chen is with the Mucosal Immunology Unit, National Institutes of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA.

    • WanJun Chen

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Yasmine Belkaid.

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DOI

https://doi.org/10.1038/ni1210-1077

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