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T cells need Nod too?

Nature Immunology volume 10, pages 12311233 (2009) | Download Citation

Nucleotide-binding oligomerization domain 2 (Nod2) is required for sensing of intracellular bacteria and subsequent inflammatory responses. Unexpectedly, new evidence suggests that Nod2 influences T helper cell signaling, proliferation and differentiation and effector responses against Toxoplasma gondii.

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Author information

Affiliations

  1. Shahram Salek-Ardakani and Michael Croft are in the Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, San Diego, California, USA.

    • Shahram Salek-Ardakani
    •  & Michael Croft

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Correspondence to Shahram Salek-Ardakani or Michael Croft.

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DOI

https://doi.org/10.1038/ni1209-1231

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