The molecular mechanisms by which the nervous system influences innate immunity to pathogens remain mysterious. Two new studies show that neuronal products modulate established innate immune signaling pathways operative in the Caenorhabditis elegans intestine.
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Kao, CY., Los, F. & Aroian, R. Nervous about immunity: neuronal signals control innate immune system. Nat Immunol 9, 1329–1330 (2008). https://doi.org/10.1038/ni1208-1329
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DOI: https://doi.org/10.1038/ni1208-1329
