The protein kinase NIK is regulated by a complex of ubiquitin ligases that destroys it. When NIK-activating receptors are triggered, the ubiquitin ligase complex self-destructs.
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Wallach, D., Kovalenko, A. Self-termination of the terminator. Nat Immunol 9, 1325–1327 (2008). https://doi.org/10.1038/ni1208-1325
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DOI: https://doi.org/10.1038/ni1208-1325
