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Unexpected partnership between IL-15 and DAP10

Interleukin 15 (IL-15) is essential for natural killer (NK) cell development and function, and the adaptor DAP10 transmits important signals in NK cells. New work shows that IL-15 and DAP10 cross regulate each other.

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Figure 1: IL-15 and DAP10 cross-regulation.

Kim Caesar

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Colucci, F. Unexpected partnership between IL-15 and DAP10. Nat Immunol 8, 1289–1291 (2007). https://doi.org/10.1038/ni1207-1289

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