The source of Langerhans cells is controversial. New data show that the repopulation of these cells depends on how and to what extent, they are depleted from the skin.
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Lucas, A., MacPherson, G. Langerhans cells: immigrants or residents?. Nat Immunol 3, 1125–1126 (2002). https://doi.org/10.1038/ni1202-1125
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DOI: https://doi.org/10.1038/ni1202-1125