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Interferon with dendritic cells?

Specialized mouse DCs exist that can recognize the presence of viral pathogens. New evidence shows that these DCs respond by secreting massive amounts of type I IFNs, which may provoke systemic resistance to such pathogens.

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Figure 1: MIPCs affect innate and adaptive defense against infection.

Bob Crimi

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Tough, D., Kamath, A. Interferon with dendritic cells?. Nat Immunol 2, 1098–1100 (2001). https://doi.org/10.1038/ni1201-1098

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