A flurry of studies has suggested the importance of the actin regulator coronin 1A in lymphocyte development. Now, mutants of this regulator are shown to cause immunodeficiency in both mice and humans.
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Hogquist, K. Immunodeficiency: when T cells are stuck at home. Nat Immunol 9, 1207–1208 (2008). https://doi.org/10.1038/ni1108-1207
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DOI: https://doi.org/10.1038/ni1108-1207
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