News & Views | Published:

Slick signaling

Nature Immunologyvolume 3pages10581059 (2002) | Download Citation

Subjects

Lipid second messengers are thought to be important in T cell activation. Two studies show the spatial-temporal organization of these lipids during immunological synapse formation and raise new questions about their functions.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Cantley, L.C. Science 296, 1655–1657 (2002).

  2. 2

    Harriague & Bismuth, G. Nature Immunol. 3, 1090–1096 (2002).

  3. 3

    Costello, P.S., Gallagher, M. & Cantrell, D.A. Nature Immunol. 3, 1082–1089 (2002).

  4. 4

    Rameh, L.E. & Cantley, L.C. J. Biol. Chem. 274, 8347–8350 (1999).

  5. 5

    Fruman, D.A., Rameh, L.E. & Cantley, L.C. Cell 97, 817–820 (1999).

  6. 6

    Hurley, J.H. & Meyer, T. Curr. Opin. Cell Biol. 13, 146–152 (2001).

  7. 7

    Teruel, M.N. & Meyer, T. Cell 103, 181–184 (2000).

  8. 8

    Shaw, A.S. Immunity 15, 683–686 (2001).

  9. 9

    Lee, K.H. et al. Science 295, 1539–1542 (2002).

  10. 10

    Ward, S.G. & Cantrell, D.A. Curr. Opin. Immunol. 13, 332–338 (2001).

  11. 11

    Iezzi, G., Karjalainen, K. & Lanzavecchia, A. Immunity 8, 89–95 (1998).

  12. 12

    van Stipdonk, M.J., Lemmens, E.E. & Schoenberger, S.P. Nature Immunol 2, 423–429 (2001).

Download references

Author information

Affiliations

  1. Washington University School of Medicine, St. Louis, MO 63110, USA

    • Andrey S.-Y. Shaw

Authors

  1. Search for Andrey S.-Y. Shaw in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/ni1102-1058

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing