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Signaling for cytotoxicity

Nature Immunology volume 1, pages 372374 (2000) | Download Citation

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Once natural killer cells identify their targets they engage their lysis machinery. Spontaneous, unlike antibody-dependent, cytotoxicity predominantly uses a Ras-independent pathway to accomplish this activation.

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References

  1. 1.

    et al. Nature Immunol. 1, 419– 425 (2000).

  2. 2.

    et al. J. Exp. Med. 186, 1965– 1974 (1997).

  3. 3.

    Curr. Top. Microbiol. Immunol. 230, 63– 88 (1998).

  4. 4.

    , , , & J. Immunol. 162, 3148–3152 (1999).

  5. 5.

    , , , & Ann. NY Acad. Sci. 766, 209–213 (1994).

  6. 6.

    et al. J. Immunol. 164, 2272– 2276 (2000).

  7. 7.

    et al. Immunity 12, 7–16 (2000).

  8. 8.

    et al. J. Exp. Med. 188, 549– 559 (1998).

  9. 9.

    , , , , & Proc. Natl Acad. Sci. USA 97, 10923–10929 (2000).

  10. 10.

    , , , , & Mol. Cell. Biol. 20, 5469–5478 (2000).

  11. 11.

    Science 285, 730–732 ( 1999).

  12. 12.

    et al. J. Immunol. 163, 4651– 4654 (1999).

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Author information

Affiliations

  1. Kimmel Cancer Center, Jefferson Medical College, Department of Microbiology and Immunology, BLSB 750, 233 S. 10th Street, Philadelphia, PA 19107, USA. bperussia@hendrix.jci.tju.edu

    • Bice Perussia

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DOI

https://doi.org/10.1038/80808

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