B cell maturation is affected by factors found in the microenvironment of the bone marrow. A new tachykinin neuropeptide family member, HK-1, and TSLP both seem to aid the pre-B cell stage.
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Bob Crimi
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Dorshkind, K. Understanding how pre-B cells come of age. Nat Immunol 1, 369–370 (2000). https://doi.org/10.1038/80802
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DOI: https://doi.org/10.1038/80802
