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RAPping production of type I interferon in pDCs through mTOR

Nature Immunology volume 9, pages 10971099 (2008) | Download Citation

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The production of type I interferon—the first line of defense against virus infection and critical for innate immunity—in plasmacytoid dendritic cells relies on the mammalian target of rapamycin.

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Author information

Affiliations

  1. Mauro Costa-Mattioli and Nahum Sonenberg are with the Department of Biochemistry and the McGill Cancer Centre, McGill University, Montreal, Quebec H3G 1Y6, Canada.  nahum.sonenberg@mcgill.ca

    • Mauro Costa-Mattioli
    •  & Nahum Sonenberg
  2. Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA.

    • Mauro Costa-Mattioli

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DOI

https://doi.org/10.1038/ni1008-1097

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