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Dendritic cells: caspases keep them young

Dendritic cell maturation leading to efficient antigen presentation is a central event that triggers adaptive immune responses. This maturation process seems to be regulated by the AP-1 adaptor proteins through the action of caspases.

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Figure 1: Caspases control DC maturation status.

Katie Ris

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Jensen, P. Dendritic cells: caspases keep them young. Nat Immunol 6, 968–969 (2005). https://doi.org/10.1038/ni1005-968

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