Immunohomeostasis prevents pathology resulting from immune activation. Two new studies link its regulation with the activation of the aryl hydrocarbon receptor, a known mediator of the toxic effects of xenobiotic ligands, in a subset of T lymphocytes.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Apetoh, L. et al. Nat. Immunol. 11, 854–861 (2010).
Gandhi, R. et al. Nat. Immunol. 11, 846–853 (2010).
Stumhofer, J.S. et al. Nat. Immunol. 7, 937–945 (2006).
Saraiva, M. & O'Garra, A. Nat. Rev. Immunol. 10, 170–181 (2010).
Anderson, C.F., Oukka, M., Kuchroo, V.J. & Sacks, D. J. Exp. Med. 204, 285–297 (2007).
Jankovic, D. et al. J. Exp. Med. 204, 273–283 (2007).
Quintana, F.J. et al. Nature 453, 65–71 (2008).
Veldhoen, M. et al. Nature 453, 106–109 (2008).
Funatake, C.J. et al. J. Immunotoxicol. 6, 194–203 (2009).
Koch, M.A. et al. Nat. Immunol. 10, 595–602 (2009).
Zheng, Y. et al. Nature 458, 351–356 (2009).
Veldhoen, M., Hirota, K., Christensen, J., O'Garra, A. & Stockinger, B. J. Exp. Med. 206, 43–49 (2009).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Veldhoen, M. A toxin-sensitive receptor able to reduce immunopathology. Nat Immunol 11, 779–781 (2010). https://doi.org/10.1038/ni0910-779
Issue Date:
DOI: https://doi.org/10.1038/ni0910-779
