Natural killer T cells acquire their unique phenotype and characteristics during development in the thymus. Evidence suggests that the transcription factor PLZF has a unique function in the development of these cells and their acquisition of 'innate-like' characteristics.
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Gapin, L. The making of NKT cells. Nat Immunol 9, 1009–1011 (2008). https://doi.org/10.1038/ni0908-1009
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DOI: https://doi.org/10.1038/ni0908-1009
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