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NKT cells join the war on Lyme disease

Whether natural killer T cells recognize antigens derived from dangerous pathogens remains unclear. New data demonstrate that a glycolipid from Borrelia burgdorferi, the causative agent of Lyme disease, directly stimulates mouse and human natural killer T cells.

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Figure 1: Activation of NKT cells by B. burgdorferi infection.

Kim Caesar

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Godfrey, D., Berzins, S. NKT cells join the war on Lyme disease. Nat Immunol 7, 904–906 (2006). https://doi.org/10.1038/ni0906-904

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