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Does AID need another aid?

AID burst onto the scene just a couple of years ago. For all of the progress, its actual mechanism for generating changes in DNA in B cells remains elusive.

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Figure 1: Proposed models for the molecular mechanisms of SHM and AID function.

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Honjo, T. Does AID need another aid?. Nat Immunol 3, 800–801 (2002). https://doi.org/10.1038/ni0902-800

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