Abstract
In this Overview, common themes of the accompanying News & Views on RA, SLE, IDDM, thyroiditis and MS are discussed. A unifying concept for the development of these and other autoimmune diseases should incorporate genetic predisposition, environmental factors and immune dysregulation.
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References
Feldmann, M. Nature Immunol. 2, 771–773 (2001).
Lipsky, P. E. Nature Immunol. 2, 764–766 (2001).
Wucherpfennig, K. W. & Eisenbarth, G. S. Nature Immunol. 2, 767–768 (2001).
Weetman, A. P. Nature Immunol. 2, 769–770 (2001).
Steinman, L. Nature Immunol. 2, 762–764 (2001).
Wakeland, E. K. Nature Immunol. 2, 802–809 (2001).
Morel, L., Tian, X. H., Croker, B. P. & Wakeland, E. K. Immunity 11, 131–139 (1999).
Todd, J. A., Bell, J. I. & McDevitt, H. O. Nature 329, 599–604 (1987).
Ridgway, W. M., Fasso, M. & Fathman, C. G. Science 284, 749–751 (1999)
Steere, A. C., Gross, D., Meyer, A. L. & Huber, B. T. J. Autoimmunity 16, 263–268 (2001).
James, J. A. & Harley, J. B. Immunol. Rev. 164, 185–200 (1998).
Surh, C. D. & Sprent, J. J. Exp. Med. 192, 9–14 (2000).
Stockinger, B. Adv. Immunol. 71, 229–265 (1999).
Straus, S. E., Sneller, M., Lenardo, M. J., Puck, J. M. & Strober, W. Ann. Intern. Med. 130, 591–601 (1999).
Refaeli, Y., Van Parijs, L. & Abbas, A. K. Immunol. Rev. 169, 273–282 (1999).
Powrie, F. Nature Immunol. 2, 816–822 (2001).
Shevach, E. M. J. Exp. Med. 193, 41–46 (2001).
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Ermann, J., Fathman, C. Autoimmune diseases: genes, bugs and failed regulation. Nat Immunol 2, 759–761 (2001). https://doi.org/10.1038/ni0901-759
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DOI: https://doi.org/10.1038/ni0901-759
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